Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 3 Reviews
8.3
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Vitamin A (Beta-Carotene, Organic Food Blend)
360 mcg
40%
Vitamin C (from Organic Food Blend)
45 mg
50%
Vitamin E (from Organic Food Blend)
6 mg
40%
Thiamin (Vitamin B1 from Organic Food Blend)
0.2 mg
17%
Riboflavin (Vitamin B2 from Organic Food Blend)
0.2 mg
15%
Niacin (from Organic Food Blend)
3 mg
19%
Vitamin B6 (from Organic Food Blend)
1 mg
59%
Folate (from Organic Food Blend)
80 mcg DFE
20%
Biotin (from Organic Food Blend)
2,500 mcg
8333%
Pantothenic Acid (from Organic Food Blend)
1 mg
20%
Zinc (from Organic Food Blend)
0.5 mg
5%
Selenium (from Organic Food Blend)
12 mcg
22%
Manganese (from Organic Food Blend)
0.1 mg
4%
Chromium (from Organic Food Blend)
35 mcg
100%
Silica (from Organic Bamboo Extract, standardized to 75% Silica)
10 mg
+
Organic Food BlendOrganic Sesbania grandiflora (leaf), Organic Amla Berry (fruit), Organic Apple (fruit), Organic Guava (fruit &leaf), Organic Annatto (fruit & seed), Organic Holy Basil (leaf), Organic Lemon (fruit & peel), Organic Moringa (leaf), Organic Beet (root), Organic Broccoli (stalk & flower), Organic Carrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry (fruit), Organic Cherry (fruit), Organic Blackberry (fruit), Organic Green Bell Pepper (fruit), Organic Brussels Sprout (leaf), Organic Ginger (root), Organic Blueberry (fruit), Organic Garlic (bulb), Organic Green Onion (bulb), Organic Raspberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem), Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd), Organic Celery (stalk), Organic Asparagus (flower & stem)
710 mg
+
Organic Beauty BlendOrganic Green Tea Extract (leaf), Organic Pomegranate Extract [standardized to 50% Polyphenols] (fruit), Organic Citrus Bioflavonoids (fruit & peel), Organic Rooibos Extract (leaf), Organic Bamboo Extract (shoot)
194 mg
+
Organic Turmeric (root)
50 mg
+
Top Medical Research Studies
We investigated whether collagen supplements could ease pain and improve quality of life for patients with knee meniscus issues. This randomized, double-blind, placebo-controlled study involved 32 participants, half receiving collagen and half a placebo.
After eight weeks, we noted that those taking collagen reported reduced pain and enhanced quality of life, along with improvements in some physical tests. While the results are promising, more extensive studies are needed to explore long-term benefits and outcomes for different patient groups.
After eight weeks, we noted that those taking collagen reported reduced pain and enhanced quality of life, along with improvements in some physical tests. While the results are promising, more extensive studies are needed to explore long-term benefits and outcomes for different patient groups.
Read More
8
We investigated the effects of specific collagen peptides on knee pain in athletes experiencing functional issues. Over 12 weeks, 139 participants took either 5 g of these peptides or a placebo daily.
Participants reported a noticeable reduction in activity-related pain, which was confirmed by physicians.
While resting pain also improved, it wasn't statistically significant. Additionally, those taking collagen needed fewer additional treatments. Overall, collagen peptides appear to be an effective option for managing knee pain during physical activity.
Participants reported a noticeable reduction in activity-related pain, which was confirmed by physicians.
While resting pain also improved, it wasn't statistically significant. Additionally, those taking collagen needed fewer additional treatments. Overall, collagen peptides appear to be an effective option for managing knee pain during physical activity.
Read More
9
This study set out to determine if oral collagen supplements could help treat knee pain linked to osteoarthritis caused by ACL injury in rats.
We found that different types of collagen, especially the protease-soluble chicken type II collagen, not only reduced pain sensitivity but also improved cartilage health.
Rats given collagen showed significant improvements compared to those who didn't receive it, leading to better joint function and less inflammation.
Overall, collagen treatment appears beneficial for managing knee pain related to osteoarthritis.
We found that different types of collagen, especially the protease-soluble chicken type II collagen, not only reduced pain sensitivity but also improved cartilage health.
Rats given collagen showed significant improvements compared to those who didn't receive it, leading to better joint function and less inflammation.
Overall, collagen treatment appears beneficial for managing knee pain related to osteoarthritis.
Read More
Most Useful Reviews
9
Knee crunching resolved
3 people found this helpful
This collagen is ideal for me as it is vegan and organic, requiring only 2 capsules per day! The jar lasted a month, and remarkably, my knees have stopped crunching, which had troubled me for over seven years!
Read More
7.5
Knee creaking alleviated
1 people found this helpful
This fantastic vegan product has prevented my knees from creaking; it also possesses oil for lubrication.
Read More
6
Helpful for knee issues
While this is not straightforward collagen, it seems to alleviate my husband's knee issues. The capsules are a bit large, making them slightly difficult to take, but overall, it offers fair value for a reasonable price.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
- All Researches
We investigated the effects of a dietary supplement containing hydrolyzed collagen, chondroitin sulfate, glucosamine, turmeric extract, and devil's claw on knee pain and function in osteoarthritis patients.
In a study with 186 participants over six months, they reported a significant decrease in pain and improved joint function. Measures showed noticeable pain relief at both three and six months, as well as enhancements in overall functioning.
Comfortingly, there were no severe side effects noted during the observation period.
In a study with 186 participants over six months, they reported a significant decrease in pain and improved joint function. Measures showed noticeable pain relief at both three and six months, as well as enhancements in overall functioning.
Comfortingly, there were no severe side effects noted during the observation period.
Read More
9
This study set out to determine if oral collagen supplements could help treat knee pain linked to osteoarthritis caused by ACL injury in rats.
We found that different types of collagen, especially the protease-soluble chicken type II collagen, not only reduced pain sensitivity but also improved cartilage health.
Rats given collagen showed significant improvements compared to those who didn't receive it, leading to better joint function and less inflammation.
Overall, collagen treatment appears beneficial for managing knee pain related to osteoarthritis.
We found that different types of collagen, especially the protease-soluble chicken type II collagen, not only reduced pain sensitivity but also improved cartilage health.
Rats given collagen showed significant improvements compared to those who didn't receive it, leading to better joint function and less inflammation.
Overall, collagen treatment appears beneficial for managing knee pain related to osteoarthritis.
Read More
We investigated whether collagen supplements could ease pain and improve quality of life for patients with knee meniscus issues. This randomized, double-blind, placebo-controlled study involved 32 participants, half receiving collagen and half a placebo.
After eight weeks, we noted that those taking collagen reported reduced pain and enhanced quality of life, along with improvements in some physical tests. While the results are promising, more extensive studies are needed to explore long-term benefits and outcomes for different patient groups.
After eight weeks, we noted that those taking collagen reported reduced pain and enhanced quality of life, along with improvements in some physical tests. While the results are promising, more extensive studies are needed to explore long-term benefits and outcomes for different patient groups.
Read More
8
This clinical study aimed to evaluate how collagen supplements might ease knee pain related to osteoarthritis.
We involved 31 participants in a controlled setting, comparing those taking collagen with a placebo group over eight weeks.
The findings indicated that collagen supplementation led to improvements in pain levels and quality of life. Some aspects of physical function also showed positive changes, highlighting collagen's potential benefits for those suffering from knee issues.
We involved 31 participants in a controlled setting, comparing those taking collagen with a placebo group over eight weeks.
The findings indicated that collagen supplementation led to improvements in pain levels and quality of life. Some aspects of physical function also showed positive changes, highlighting collagen's potential benefits for those suffering from knee issues.
Read More
8
We conducted a study to see how effective a herbal supplement, NXT15906F6 (also known as TamaFlex), is in reducing knee pain and joint inflammation, specifically in a rat model of osteoarthritis. The rats were divided into groups and received either this supplement or a standard medication called Celecoxib over 28 days.
Post-treatment results revealed that NXT15906F6 significantly decreased joint pain and inflammation, while also improving the overall joint condition. The study showed promising signs by reducing harmful proteins that can cause joint damage. This suggests that NXT15906F6 could be a beneficial option for managing knee pain more effectively.
Post-treatment results revealed that NXT15906F6 significantly decreased joint pain and inflammation, while also improving the overall joint condition. The study showed promising signs by reducing harmful proteins that can cause joint damage. This suggests that NXT15906F6 could be a beneficial option for managing knee pain more effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Knee crunching resolved
3 people found this helpful
This collagen is ideal for me as it is vegan and organic, requiring only 2 capsules per day! The jar lasted a month, and remarkably, my knees have stopped crunching, which had troubled me for over seven years!
Read More
7.5
Knee creaking alleviated
1 people found this helpful
This fantastic vegan product has prevented my knees from creaking; it also possesses oil for lubrication.
Read More
6
Helpful for knee issues
While this is not straightforward collagen, it seems to alleviate my husband's knee issues. The capsules are a bit large, making them slightly difficult to take, but overall, it offers fair value for a reasonable price.
Read More
Frequently Asked Questions
9
Knee crunching resolved
3 people found this helpful
This collagen is ideal for me as it is vegan and organic, requiring only 2 capsules per day! The jar lasted a month, and remarkably, my knees have stopped crunching, which had troubled me for over seven years!
7.5
Knee creaking alleviated
1 people found this helpful
This fantastic vegan product has prevented my knees from creaking; it also possesses oil for lubrication.
6
Helpful for knee issues
While this is not straightforward collagen, it seems to alleviate my husband's knee issues. The capsules are a bit large, making them slightly difficult to take, but overall, it offers fair value for a reasonable price.
8
This clinical study aimed to evaluate how collagen supplements might ease knee pain related to osteoarthritis.
We involved 31 participants in a controlled setting, comparing those taking collagen with a placebo group over eight weeks.
The findings indicated that collagen supplementation led to improvements in pain levels and quality of life. Some aspects of physical function also showed positive changes, highlighting collagen's potential benefits for those suffering from knee issues.
We involved 31 participants in a controlled setting, comparing those taking collagen with a placebo group over eight weeks.
The findings indicated that collagen supplementation led to improvements in pain levels and quality of life. Some aspects of physical function also showed positive changes, highlighting collagen's potential benefits for those suffering from knee issues.
We investigated the effects of a dietary supplement containing hydrolyzed collagen, chondroitin sulfate, glucosamine, turmeric extract, and devil's claw on knee pain and function in osteoarthritis patients.
In a study with 186 participants over six months, they reported a significant decrease in pain and improved joint function. Measures showed noticeable pain relief at both three and six months, as well as enhancements in overall functioning.
Comfortingly, there were no severe side effects noted during the observation period.
In a study with 186 participants over six months, they reported a significant decrease in pain and improved joint function. Measures showed noticeable pain relief at both three and six months, as well as enhancements in overall functioning.
Comfortingly, there were no severe side effects noted during the observation period.
7
We investigated how daily collagen peptide (CP) supplementation impacts knee pain and overall function in healthy, active middle-aged adults. In a well-structured double-blind trial, participants were given either a placebo or 10 to 20 grams of CP daily over 6 to 9 months.
The results revealed that 10 grams of CP significantly improved daily activities and pain levels, particularly in those who exercised frequently. Additionally, mental and physical health scores saw positive changes with consistent CP intake. This suggests that collagen supplements can be beneficial for managing knee pain and enhancing quality of life in active adults.
The results revealed that 10 grams of CP significantly improved daily activities and pain levels, particularly in those who exercised frequently. Additionally, mental and physical health scores saw positive changes with consistent CP intake. This suggests that collagen supplements can be beneficial for managing knee pain and enhancing quality of life in active adults.
7
We examined the effectiveness of dietary supplements, including collagen, for treating knee pain in osteoarthritis patients. The review analyzed multiple studies, highlighting that while some supplements showed promising short-term benefits for pain relief, the overall quality of evidence was very low.
Notably, widely used options like glucosamine and chondroitin showed minimal impact and lacked significant long-term benefits. In the end, collagen may provide temporary relief, but it's not a guaranteed solution for everyone.
Notably, widely used options like glucosamine and chondroitin showed minimal impact and lacked significant long-term benefits. In the end, collagen may provide temporary relief, but it's not a guaranteed solution for everyone.
8
We investigated the effects of specific collagen peptides on knee pain in athletes experiencing functional issues. Over 12 weeks, 139 participants took either 5 g of these peptides or a placebo daily.
Participants reported a noticeable reduction in activity-related pain, which was confirmed by physicians.
While resting pain also improved, it wasn't statistically significant. Additionally, those taking collagen needed fewer additional treatments. Overall, collagen peptides appear to be an effective option for managing knee pain during physical activity.
Participants reported a noticeable reduction in activity-related pain, which was confirmed by physicians.
While resting pain also improved, it wasn't statistically significant. Additionally, those taking collagen needed fewer additional treatments. Overall, collagen peptides appear to be an effective option for managing knee pain during physical activity.
References
- Genç AS, Yılmaz AK, Anıl B, Korkmaz Salkılıç E, Akdemir E, et al. The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy: a randomized, double-blind, placebo-controlled study. BMC Musculoskelet Disord. 2025;26:17. 10.1186/s12891-024-08244-w
- Genç AS, Yılmaz AK, Anıl B, Korkmaz Salkılıç E, Akdemir E, et al. Effect of supplementation with type 1 and type 3 collagen peptide and type 2 hydrolyzed collagen on osteoarthritis-related pain, quality of life, and physical function: A double-blind, randomized, placebo-controlled study. Jt Dis Relat Surg. 2025;36:85. 10.52312/jdrs.2025.1965
- Puigdellívol Grifell J, Comellas Berenguer C, Steinbacher G, Kranjcec T, Álvarez Díaz P, et al. Open, Observational, Single-Arm, Multicenter Study Assessing the Effectiveness of a Dietary Supplement Containing Hydrolyzed Collagen, Chondroitin Sulfate, and Glucosamine for Osteoarthritis Pain Reduction. J Diet Suppl. 2024;21:374. 10.1080/19390211.2023.2284982
- Thomas DT, Prabhakar AJ, Eapen C, Patel VD, Palaniswamy V, et al. Comparison of Single and Combined Treatment with Exercise Therapy and Collagen Supplementation on Early Knee Arthritis among Athletes-A Quasi-Randomized Trial. Int J Environ Res Public Health. 2023;20. 10.3390/ijerph20237088
- van Dam L, Terink R, Mensink M, de Vos RJ, Zwerver J. The JUMPFOOD study: additional effect of hydrolyzed collagen and vitamin C to exercise treatment for patellar tendinopathy (jumper's knee) in athletes-study protocol for a double-blind randomized controlled trial. Trials. 2023;24:768. 10.1186/s13063-023-07783-2
- Yves H, Herman J, Uebelhoer M, Wauquier F, Boutin-Wittrant L, et al. Oral supplementation with fish cartilage hydrolysate in an adult population suffering from knee pain and function discomfort: results from an innovative approach combining an exploratory clinical study and an ex vivo clinical investigation. BMC Musculoskelet Disord. 2023;24:748. 10.1186/s12891-023-06800-4
- Chen NF, Lin YY, Yao ZK, Tseng CC, Liu YW, et al. Oral Administration of Protease-Soluble Chicken Type II Collagen Ameliorates Anterior Cruciate Ligament Transection-Induced Osteoarthritis in Rats. Nutrients. 2023;15. 10.3390/nu15163589
- Kviatkovsky SA, Hickner RC, Cabre HE, Small SD, Ormsbee MJ. Collagen peptides supplementation improves function, pain, and physical and mental outcomes in active adults. J Int Soc Sports Nutr. 2023;20:2243252. 10.1080/15502783.2023.2243252
- Kwon SB, Chinta G, Kundimi S, Kim S, Cho YD, et al. A Blend of and Extracts Alleviates Monosodium Iodoacetate (MIA)-Induced Osteoarthritic Pain and Joint Inflammation in Rats. J Am Nutr Assoc. 2024;43:48. 10.1080/27697061.2023.2209880
- Chen CC, Chang SS, Chang CH, Hu CC, Nakao Y, et al. Randomized, double-blind, four-arm pilot study on the effects of chicken essence and type II collagen hydrolysate on joint, bone, and muscle functions. Nutr J. 2023;22:17. 10.1186/s12937-023-00837-w
- Shavlovskaya OA. [Complex effects of physical exertion with dietary supplements Cartilox in pain syndrome effectiveness and safety evaluation]. Vopr Kurortol Fizioter Lech Fiz Kult. 2022;99:20. 10.17116/kurort20229904120
- Mohammed A, He S. A Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy of a Hydrolyzed Chicken Collagen Type II Supplement in Alleviating Joint Discomfort. Nutrients. 2021;13. 10.3390/nu13072454
- Lee HS, Oh KJ, Moon YW, In Y, Lee HJ, et al. Intra-articular Injection of Type I Atelocollagen to Alleviate Knee Pain: A Double-Blind, Randomized Controlled Trial. Cartilage. 2021;13:342S. 10.1177/1947603519865304
- García-Coronado JM, Martínez-Olvera L, Elizondo-Omaña RE, Acosta-Olivo CA, Vilchez-Cavazos F, et al. Effect of collagen supplementation on osteoarthritis symptoms: a meta-analysis of randomized placebo-controlled trials. Int Orthop. 2019;43:531. 10.1007/s00264-018-4211-5
- Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ. Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis. Br J Sports Med. 2018;52:167. 10.1136/bjsports-2016-097333
- Zdzieblik D, Oesser S, Gollhofer A, König D. Improvement of activity-related knee joint discomfort following supplementation of specific collagen peptides. Appl Physiol Nutr Metab. 2017;42:588. 10.1139/apnm-2016-0390
